PM413. Metabolic Syndrome in Patients With Schizophrenia Receiving Long-Term Treatment With Lurasidone, Quetiapine XR, or Risperidone
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منابع مشابه
PM412. Emergence of Tardive Dyskinesia upon Clozapine Treatment: A Case Report
s | 49 Improvements in PANSS scores following OL PP1M were similar in recent RIS/PALI (mean [SD] of -18.3 [17.96]) and no prior RIS/PALI (-21.1 [16.40]) subgroups at OL endpoint. Relapse-free rates during DB phase were comparable across recent RIS/PALI (PP3M: 89.7%; PP1M: 87.1%, 95% CI for difference: [-4.7; 10.0]) and no RIS/PALI subgroups (PP3M: 91.6%; PP1M: 90.8%, 95% CI for difference: [-4....
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We previously reported that treatment with 160mg/d of lurasidone improved cognitive performance in a manner superior to placebo, quetiapine XR 600mg/d, and lurasidone 80mg/d, based on a 6-week randomized trial of patients with an acute exacerbation of schizophrenia. The objective of this post-hoc analysis was to explore the cognitive and functional performance of patients whose final doses of l...
متن کاملDaytime sleepiness associated with lurasidone and quetiapine XR: results from a randomized double-blind, placebo-controlled trial in patients with schizophrenia
OBJECTIVE The aim of this analysis was to compare the effects of 2 atypical antipsychotic agents, lurasidone (80 mg/d or 160 mg/d) and quetiapine XR (600 mg/d), on daytime alertness, and to evaluate the effects of daytime sleepiness on treatment outcomes in patients with an acute exacerbation of schizophrenia. METHODS Patients who met Diagnostic and Statistical Manual of Mental Disorders, 4th...
متن کاملLurasidone (LatudaTM) tablets for the treatment of schizophrenia in adults
(In this document lurasidone doses are expressed as lurasidone base. Equivalent doses of lurasidone base and the hydrochloride salt are 18.5mg=20mg, 37mg=40mg, 74mg=80mg, 111mg=120mg and 148mg=160mg). Dosing The recommended starting dose is 37 mg once daily with food. No initial dose titration is required and the maximum dose is 148 mg daily. Dose increase is based on physician judgement and ob...
متن کاملClinical and Cost Consequences of Metabolic Effects of Lurasidone Versus Other Atypical Antipsychotics in Schizophrenia
Objective: To estimate the economic burden of hyperglycemia and diabetes associated with lurasidone versus other atypical antipsychotics in schizophrenia. Methods: A discrete event simulation model was developed to conduct the analysis from both US payer and societal perspectives over a 3-year timeframe. The model, based on the values of metabolic parameters at 1 year of treatment, identified p...
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